Individuals Battling Lymphoedema Find Benefits in Cannabinoid Products

Individuals Battling Lymphoedema Find Benefits in Cannabinoid Products

The lymphatic system is crucial to keeping the body healthy. In fact, this system is a part of the Immune System. It is responsible for circulating protein-rich lymph fluid throughout the body, collecting bacteria, viruses and waste products. The main role of the lymphatic system is to carry this fluid and harmful substances through the lymph vessels, which lead to lymph nodes. The wastes are then filtered out by lymphocytes (infection-fighting cells that live inside the lymph nodes) and ultimately flushed from the body. Lymph nodes often cluster in areas where the lymphatic vessels branch off, such as the neck, armpits, and groin. 

Causes of Lymphoedema

    Lymphoedema occurs when your lymph vessels are unable to adequately drain lymph fluid, usually from an arm or leg. Lymphoedema can be either primary or secondary. This condition rarely occurs on its own (primary lymphoedema). Generally, medical professionals determine the cause by another disease or condition (secondary lymphoedema). 

Primary Lymphoedema

Medical professionals agree that Primary Lymphoedema remains rare. This type is an inherited condition caused by problems with the development of lymph vessels in the body. Specific causes of primary lymphoedema vary. Milroy’s disease (congenital lymphoedema) acts as a disorder beginning in infancy and causes lymph nodes to form abnormally. Meige’s disease (lymphoedema praecox) exerts lymphoedema symptoms around puberty or during pregnancy. However, symptoms possibly occur as late as age 35. Late-onset lymphoedema (lymphoedema tarda) occurs rarely and usually begins after age 35.

Secondary Lymphoedema

Medical professionals warn that conditions or procedures that cause damage to the Lymph nodes or Lymph vessels exhibit the possibility of causing Lymphoedema. For example, lymph nodes may be removed to check for spread of breast cancer, and lymph nodes may be injured in surgery that involves blood vessels in your limbs. Radiation can cause scarring and inflammation of the lymph nodes or lymph vessels. Severe conditions such as cancer run the risk of causing Lymphoedema as well. If cancer cells block lymphatic vessels, lymphoedema may result. For instance, a tumor growing near a lymph node or lymph vessel could enlarge enough to block the flow of the lymph fluid. Infections of the lymph nodes or parasites can restrict the flow of lymph fluid. Infection-related lymphoedema is most common in tropical and subtropical regions and is more likely to occur in developing countries.

Symptoms of Lymphoedema 

    Symptoms of Lymphoedema 1 generally affect only the afflicted limb and include swelling, aching or pain/inflammation, limited range of motion, a feeling of heaviness/tightness, recurring infections, and hardening of skin (Fibrosis). The swelling caused by lymphoedema ranges from mild, hardly noticeable changes in the size of your arm or leg to extreme changes that make the limb difficult to use. Lymphoedema caused by cancer treatment may not occur until months or years after treatment. 

Cannabinoids Aid in the Management of Symptoms

    While Lymphoedema can not be completely cured, the symptoms can be managed with proper care. Precautions such as light exercise, bandaging, massaging, pneumatic compresses, and compression garments all offer benefits for this condition. 

Cannabinoids Reduce Inflammation and the Spread of Fibrosis 

Cannabinoids generally remain free from the adverse effects associated with NSAIDs. Consequently, clinical development of these Cannabinoids provides a new approach to treatment of diseases characterized by acute and chronic inflammation and fibrosis. In studies, researchers showed that CBD induced both apoptosis and autophagy-induced death in cancer cells, indicating the ability to control the spread of cancerous and fibrotic cells. 

Cannabidiol (CBD) functions as a potent anti-inflammatory agent. Effective in suppressing IFN-γ and TNF-α (pro-inflammatory cytokines) production and progression of autoimmune conditions by inhibition of T cell proliferation, Cannabidiol has spiked interest in the medical research community. These findings provide compelling evidence for the use of CBD in the treatment of inflammation and neuroprotection both in terms of its efficacy and safety. The anti inflammatory action of CBD on cisplatin-induced inflammation, and tissue injury in the kidney was studied using an established mouse model of cisplatin-induced nephropathy. CBD treatment reduced mRNA expression of those pro-inflammatory cytokines. Interestingly, several markers of nephrotoxicity also exhibited reduction. This information indicates that Cannabidiol acts as an effective anti inflammatory.

Cannabinoids Fight Dangerous Infections

Cannabis has long been known to contain antibacterial cannabinoids. All five major cannabinoids: Cannabidiol, Cannabichromene, Cannabigerol, ∆9- Tetrahydrocannabinol and Cannabinol showed potent activity against a variety of methicillin-resistant Staphylococcus aureus (MRSA) strains (Appendino et al., 2008). Additionally, antibacterial activity of Cannabichromene and its isomers showed strong antimicrobial activity against gram-positive, gram-negative, acid-fast bacteria, yeast-like fungi, filamentous fungi and a dermatophyte (Turner et al. 1981).  Certain Cannabinoids also exert microbicidal (Microbe killing) activity on gram-positive bacteria such as Baccilus subtilus, Baccilus pumilus, Staphylococcus aureus, Micrococcus flavus, Clostridium sporogens, Enterococcus faecium, and Streptococcus salivarius; and on gram-negative bacteria like Proteus vulgaris, Bordetella bronchioseptica, Pectobacterium carotovorum, and Pseudomonas savastanoi; as well as in some fungi, such as Aspergillus niger. However, it should be highlighted that the microbicidal effect of cannabinoids has only been seen in experiments in vitro.

Try Cannabinoid Products for Your Relief!

    Cannabinoids may be an option for your Lymphoedema symptom management. Find products aimed at providing relief in our shop or at one of our retail locations.