Diverticulitis is a digestive disorder that is responsible for approximately 200,000 hospitalizations in the United States each year. Small pouches or sacs, Diverticulum, form and push outwards on the weak spots in the wall of the colon. Diverticulitis will occur when these sacs become inflamed, often causing complications. Doctors warn chronic sufferers of Diverticulitis to be aware of the possibility of abscesses forming, perforation (tearing) in the colon, inflammation and infection of the abdomen, and intestinal obstructions.
Cannabinoid Products Offer Relief
Even if an individual with Diverticulitis avoids the serious complications mentioned above, many symptoms will persist. The most common symptom experienced will be pain due to inflammation in the digestive tract and colon. Other common symptoms will include nausea, vomiting, fever, tenderness of the abdomen, and constipation or less commonly diarrhea.
Digestive Inflammatory Relief with Cannabinoids
In the Gastrointestinal System, CB1 and CB2 receptors exist in all layers of intestinal sections. Numerous studies conducted with mouse models have demonstrated a relationship between the Endocannabinoid System and regulation of gut inflammation. Recent experimental data supports an important role for natural Cannabinoids in Gastrointestinal Diseases (Schicho and Storr, 2012). In fact, researchers propose Cannabis to treat Gastrointestinal conditions that range from infections and inflammation to disorders of abdominal pain. Data gathered in trials demonstrated that Cannabinoids may hinder the release of a wide class of pro-inflammatory mediators (molecules that promote inflammation). Even Cannabichromene exhibited the ability to normalize intestinal motility in the inflamed gut.
Controlling Nausea with Cannabinoids
Additionally, considerable amounts of evidence suggest that manipulation of the Endocannabinoid regulates vomiting and nausea. In fact, CB1(Cannabinoid Receptor 1) agonism suppresses vomiting. As far back as 1995, evidence was beginning to suggest that Cannabis-based medicines may be effective in treating nausea and vomiting in children. Abrahamov et al. (1995) Consequently, pharmaceutical companies such as GW Pharmaceuticals, have active applications for the use of Cannabidiol as an antiemetic, antinausea treatment. Other applicants have named CBN, CBC, THC and several derivatives as possible treatments of nausea and vomiting.
Cannabinoids Offer Endless Possibilities
Currently, several pharmaceutical companies own patents for the use of Cannabinoid compositions for the treatment of several ailments. In fact, GW Pharmaceuticals owns the patents that outlines a method of treatment of constipation comprising administering to a subject in need thereof a combination of the cannabinoids cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC). Other patents for Cannabinoids outline their anti-inflammatory, antiemetic, anticonvulsant, antioxidant, appetite inducing, anxiolytic and neuroprotectant properties. Studies patents and clinical trials have outlined countless other benefits as well.